| NO. | INTERMEDIATE NAME(PHARMACUETICAL) | APPLICATION | CAS NO. |
|---|---|---|---|
| 1 | 5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile | Vericiguat Intermediate | 1350653-26-7 |
| 2 | 1H-Pyrazole-3-carboxylic acid, 5-(acetylamino) | Darolutamide Intermediate | 949034-45-1 |
| 3 | 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine | Abemaciclib Intermediate | 1180132-17-5 |
| 4 | 2-Pyridylacetic acid hydrochloride | Perampanel Intermediate | 16179-97-8 |
| 5 | (2-Cyanophenyl)acetic acid | Perampanel Intermediate | 18698-99-2 |
| 6 | 1R)-3-Chloro-1-phenyl-propan-1-ol | Dapoxetine HCl Intermediate | 100306-33-0 |
| 7 | 4-(4-Aminophenoxy)-N-methylpyridine-2-carboxamide | Sorafenib Tosylate Intermediate | 284462-37-9 |
| 8 | Methyl2-ethoxy-1-((2'-(N-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)- 1H-benzo[d]imidazole-7-carboxylate | Azilsartan kamedoxomil Intermediate | 147403-65-4 |
| 9 | Ripasudil HCl Dihydrate | Ripasudil HCl | 887375-67-9 |
| 10 | tert-Butyl6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimid | Ripasudil R1 | 289042-12-2 |
| 11 | 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methanol | Rosuvastatin Calcium Intermediate Z7 | 147118-36-3 |
| 12 | 2-Butyl-4-spirocyclopentane-2-imidazolin-5-one hydrochloride | Irbesartan Intermediate | 151257-01-1 |
| 13 | Ethyl (3R,4R,5S)-4-N-Acetylamino-5-N,N-diallylamino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate | Oseltamiv Intermediate | 651324-09-3 |
| 14 | 4'-Methyl-2-cyanobiphenyl | 4'-Methyl-2-cyanobiphenyl | 114772-53-1 |
| 15 | N-[(2'-cyano[1,1'biphenyl]-4-yl)methyl]-methyl ester L-valine monohydrochloride | Valsartan Intermediate | 482577-59-3 |
| 16 | (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone | (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone | 189028-93-1 |
Pharmaceutical Intermediate
Pharmaceutical Intermediate are fine chemicals that are intermediate compounds produced during the production of active pharmaceutical ingredients (APIs).
Description
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LACOSAMIDE CAS: 175481-36-4
Lacosamide is an anticonvulsant and analgesic compound used for the treatment of partial-onset seizures and neuropathic pain. It can also used for the treatment of status epilepticus. Its analgesic effect is mediated by its inhibitory effect on sodium channels, which leads to neural membrane depolarization. Its interaction with the collapsin-response mediator protein 2 (CRMP-2 alias DRP-2) may also facilitate the above process, although the detailed mechanism remains to be elucidated.
